The recent appointment of Andrius Kubilius as the first-ever Commissioner for Defence remarks the importance of the industrial defence strategy for the Commission Von der Leyen II. However, the complementarity between this new portfolio and the High Representative of the Union for Foreign Affairs and Security Policy/ Vice President of the European Commission (HR/VP) is still uncertain. Overlaps and conflicts of competence could undermine the role of the HR/VP and cause unnecessary delays and upset among the Member States. This leads to two fundamental questions: Where are conflicts likely to emerge between these roles, and what mechanism can push forward better coordination to strengthen European defence?